Retatrutide Injections for Medical Weight Loss
At Preferred Regen ATL, we are proud to offer Retatrutide, an exciting new advancement in medical weight loss injections. Retatrutide is a powerful therapy that targets multiple pathways to support significant weight loss and improve overall metabolic health. Designed for individuals who want to achieve meaningful and lasting results, this triple-action medication is emerging as one of the most promising options available.
How Retatrutide Works
Retatrutide is a triple hormone receptor agonist, sometimes called a “tri-agonist.” It activates three different hormone receptors in the body:
GLP-1 Receptor
(Also targeted by semaglutide)
- Increases insulin when blood sugar is high.
- Decreases glucagon (which raises blood sugar).
- Slows stomach emptying → makes you feel full longer.
- Reduces appetite by acting on the brain.
GIP Receptor
(Also targeted by tirzepatide)
- Increases insulin secretion.
- May improve how fat is processed in the body.
- Further reduces appetite.
Glucagon Receptor
(Unique to retatrutide compared to semaglutide and tirzepatide.)
- Increases energy expenditure → helps you burn more calories.
- May help mobilize fat stores.
Why is this combination powerful?
By hitting all three receptors at once, retatrutide aims to:
✅ Strongly suppress appetite.
✅ Improve how your body uses and stores energy.
✅ Increase calorie burning, which is not a major effect of the other two drugs.
This multi-pathway approach is why early studies show up to ~24% body weight loss, which is higher than semaglutide (~15%) or tirzepatide (~20%).
Bottom line
Retatrutide is designed to reduce appetite, improve insulin function, and increase calorie burning all at once, making it potentially the most powerful weight-loss medication so far.
Proven Results
Clinical trials have shown that retatrutide can:
Lead to very significant weight loss
- Participants lost up to ~24% of their body weight after 48 weeks at the highest dose.
- This is the highest weight loss reported for a medication so far — approaching results seen with bariatric surgery.
Improve metabolic health
- Improved blood sugar control (important for people with type 2 diabetes or prediabetes).
- Improved insulin sensitivity.
- Reduced cholesterol and triglycerides.
Reduce waist circumference and body fat
- Participants had a significant drop in waist size and overall fat mass.
- Suggests not just weight loss but specifically reduction in harmful visceral (belly) fat.
Increase energy expenditure
- Thanks to its glucagon receptor activation, retatrutide may help the body burn more calories at rest — a unique feature compared to other weight loss medications.
Schedule a Consultation
Discover how Retatrutide can benefit you, schedule a consultation with our expert team at Preferred Regen.